Cynomolgus baff
WebB-cell activating factor (BAFF), also called B-lymphocyte stimulator (BLyS), is required for the development and survival of B cells. In systemic lupus erythematosus patients, BAFF is overexpressed, which may cause autoimmune B cell proliferation and survival. Belimumab binds to BAFF and prevents it from binding to B cells. WebFeb 1, 2006 · BAFF (also known as BLyS, THANK, TALL-1, TNFSF13B, and zTNF4) is a member of the tumor necrosis factor (TNF) ligand superfamily and has been shown to stimulate proliferation and to induce maturation of B lymphocytes. 1, 2, 3, 4 Mice deficient in BAFF have reduced B-cell numbers and antigenic responses. 5, 6 Conversely, …
Cynomolgus baff
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WebDNA sequence encoding Cynomolgus BAFF/TNFSF13B/CD257 Trimer including a N-His-Avi,N-Flag tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. WebFeb 22, 2024 · For cynomolgus monkey CD19, the final antibody concentrations are 5 nM, 1 nM, 200 pM and 40 pM, and the final cell dilutions of 100×10 6 cells/mL down to approximately 4,200 cells/mL. The plate is incubated on a plate shaker at 37° C. for 3-4 days for human CD19 and 2 days for cynomolgus monkey CD19 to allow binding to reach …
WebBCMA BCA-C5253 Cynomolgus BCMA(Biotin-labeled) BCA-C82F4 Cynomolgus BAFF BAF-H4218 Human BAFF BAF-H4268 Human BAFF BAF-H5248 Human BAFF (Biotin-labeled) BAF-H82F3 Human BAFF (FITC) BAF-HF268 Human BAFF (Biotin-labeled) BAF-H82Q2 Human BAFFR BAR-H5257 Human BAFFR BAR-M5259 Mouse BAFFR (Biotin … WebCynomolgus BAFFR/TNFRSF13C Protein. ... B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17 ...
WebStructure Aided design & Multiplex Screening (SAMS) Learn more about SAMS; COMPANY WebRecombinant Biotinylated Cynomolgus BAFF/TNFSF13B/CD257 Trimer Protein is expressed from Expi293 with His tag and Flag tag and Avi tag at the N-terminal.It contains Thr141-Leu285 Biotinylated Cynomolgus BAFF Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
WebTibulizumab (LY 3090106) is a tetravalent bispecific monoclonal antibody targeting B-cell activating factor (BAFF) and IL-17A with Kd values of 60 pM and 14 pM, respectively. Tibulizumab can be used for autoimmune disease research. For research use only. We do not sell to patients. Tibulizumab Chemical Structure CAS No. : 1849636-24-3
WebBAFF Receptor (B-cell activating factor receptor, BAFF-R), also known as TNFRSF13C and BR3, is a membrane protein of the TNF receptor superfamily which recognizes BAFF. … granite world namibiaWebJul 26, 2004 · BAFF, the ligand for BAFF-R is an important B-cell survival and maturation factor (reviewed in ref. 12). In accord, we report that cynomolgus monkey CD21 − … graniteworx incWebFeb 1, 2006 · BAFF (also known as BLyS), a member of the tumor necrosis factor superfamily, plays a critical role in the maturation and development of B cells. BAFF has … chinook energy calgaryWebCynoglossus cynoglossus, commonly known as the Bengal tonguesole, sometimes called the Gangetic tongue sole, is a species of tonguefish.It is commonly found in the Indian … chinook elementary school anchorage akWebBAFF Receptor is the crucial receptor for B-cell survival and also is a potent costimulator of both B and T cell activation [1] . BAFFR/TNFRSF13C Protein, Cynomolgus (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 70 amino acids (S7-G76) and is produced in HEK293 cells. MedChemExpress offers high purity BAFFR ... graniteworx edmontonWeb(iii) the HCDR1 comprises the amino acid sequence of SEQ ID NO: 3, the HCDR2 comprises the amino acid sequence of SEQ ID NO: 13, the HCDR3 comprises the amino acid sequence of SEQ granite worthington ohioWebApr 6, 2024 · It was selected based on potent T cell activation and anti-MM activity in preclinical models with favorable tolerability in cynomolgus monkey. In the ongoing first-in-human phase I... chinook energy inc stock