Cytoplasmic aconitate hydratase-like

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WebPredicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including adaxial cell; heart tube; musculature system; nervous system; and pronephric duct. Human ortholog(s) of this … WebImmunocytochemistry/ Immunofluorescence: Aconitase 1 Antibody [NBP1-87677] - Staining of human cell line U-2 OS shows localization to cytosol & mitochondria. Antibody staining is shown in green. Immunohistochemistry-Paraffin: Aconitase 1 Antibody [NBP1-87677] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Biology Free Full-Text Aconitase: To Be or not to Be Inside

WebDec 23, 2003 · Nevertheless, little is known regarding the response of aconitase to pro-oxidants within intact mitochondria. In the present study, we provide evidence that aconitase is rapidly inactivated and subsequently reactivated when isolated cardiac mitochondria are treated with H (2)O (2). Reactivation of the enzyme is dependent on the presence of the ... WebNX_P21399 - ACO1 - Cytoplasmic aconitate hydratase - Localization. Bifunctional iron sensor that switches between 2 activities depending on iron availability (PubMed:1946430, PubMed:1281544, PubMed:8041788). Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration … portland escape room beaverton

Characterization of aconitate hydratase from mitochondria and cytoplasm ...

WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves dehydration followed by hydration. Although citrate is a symmetric molecule, aconitase works specifically on the OAA end of citrate, not the end derived from acetyl ... WebAug 1, 1988 · This paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by BALB/C mice. The results show a ... WebWe show that PP2A-B'γ physically interacts with the cytoplasmic form of aconitase, a central metabolic enzyme functionally connected with mitochondrial respiration, oxidative stress responses and regulation of cell death in plants. Furthermore, PP2A-B'γ impacts ROS homeostasis by controlling the abundance of specific alternative oxidase ... optician in manasquan nj

Metabolic regulation of citrate and iron by aconitases: role ... - PubMed

WebSearch Result : 7756 hits. Entry KO len SW-score(margin) bits identity overlap best(all WebJul 8, 2024 · Enzymatic activity of aconitate hydratase (aconitase, EC 4.2.1.3) from the rat heart is localized in the cytoplasm (65%) and mitochondria (35%). Cytoplasmic and … portland espresso machine repairWebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. DrugBank ID Name Drug group Pharmacological action? Actions Details; DB06757: Manganese: approved, nutraceutical: unknown: inhibitor: Details: portland essential 38

"WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves … " - Cytoplasmic aconitate hydratase-like

Cytoplasmic aconitate hydratase-like

Cytoplasmic aconitate hydratase DrugBank Online

WebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. … Cytoplasmic aconitate hydratase. Gene. ACO1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 889. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. Feature viewer. Publications. ... SSF52016 LeuD/IlvD-like 1 hit; TIGRFAMs. TIGR01341 aconitase_1 1 hit; See more

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WebKEGG Orthology (KO) [BR:gsj00001] 09100 Metabolism 09101 Carbohydrate metabolism 00020 Citrate cycle (TCA cycle) 114372894 00630 Glyoxylate and dicarboxylate metabolism WebSpecific Function. Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, …

WebAconitate Hydratase. Aconitate hydratase (aconitase, EC4.2.1.3) is both an important Krebs cycle enzyme and a cytosolic iron sensor as described above. From: Nutrient …

Webcytoplasmic aconitate hydratase-like. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. LOC106077989 cytoplasmic aconitate hydratase-like [] Gene ID: 106077989, updated on 18-Jan-2024 ... WebJan 4, 2024 · fumarate hydratase Antibody (J-13) is a mouse monoclonal IgG 2b κ, cited in 58 publications, provided at 100 µg/ml. raised against recombinant fumarate hydratase of human origin. recommended for detection of precursor mitochondrial and cytoplasmic mature chains of fumarate hydratase of human origin by WB, IP, IF, IHC (P) and ELISA.

WebThe activity of the iron-dependent enzyme cytosolic aconitase (c-aconitase) is increased by iron. The conversion of citrate to isocitrate by c-aconitase is the first step in a three …

WebAug 4, 2024 · Therefore, it’s possible cytoplasmic aconitate hydratase may regulate energy metabolism during oogenesis as well. Evidence of cytoplasmic aconitate hydratase abundance changing in response to low pH has been documented in C. gigas, which implies that low pH alters energy metabolism . Energy metabolism would be … portland espresso machineWebJan 8, 2016 · This product is manufactured by BioVision, an Abcam company and was previously called K716 Aconitase Activity Colorimetric Assay Kit. K716-100 is the same size as the 100 test size of ab83459. Aconitase (aconitate hydratase; EC 4.2.1.3) is an iron-sulfur protein containing an [Fe4S4]2+ cluster that catalyzes the stereospecific … optician jobs in bancroft miWebSep 21, 2008 · Data on the structure, functions, regulation of activity, and expression of cytosolic and mitochondrial aconitate hydratase isoenzymes of mammals are reviewed. The role of aconitate hydratase and structurally similar iron-regulatory protein in maintenance of homeostasis of cell iron is described. Information on modifications of the … portland episodesWebCytoplasmic aconitate hydratase Synonyms. 4.2.1.3; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; IRE-BP 1; IREB1; Iron regulatory protein 1; Iron-responsive element-binding protein 1; IRP1; Gene Name ACO1 Organism Humans Amino acid … portland essential midwiferyWebJul 30, 1999 · IRP1 is a cytoplasmic aconitase when it contains a [4Fe-4S] cluster and an RNA-binding protein after complete removal of the metal center by an unknown mechanism. Human IRP1, obtained as the pure recombinant [4Fe-4S] form, is an enzyme as efficient toward cis-aconitate as the homologous mitochondrial aconitase. portland er portland txWebGene ID: 105431932, updated on 7-Sep-2024. Summary Other designations. cytoplasmic aconitate hydratase-like optician in newcastle upon tyneWebJul 12, 2024 · After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested in some textbooks and recent scientific articles. Genetic research (including the study of mutants … portland essential porch parcel