WebMar 30, 2024 · The ubiquitin-proteasome system plays an important role in acquiring resistance to rituximab and chemotherapy agents in B-cell lymphoma. 9, 10 Carfilzomib (CFZ, PR-171) is a potent, tetrapeptide ketoepoxide–based inhibitor specific for the chymotrypsin-like active site of the 20S proteasome. It was first approved for the … WebAug 20, 2009 · The lymphoma nowadays included in the WHO classification with the name “mantle cell lymphoma” (MCL) 1 was first described by K. Lennert more than 30 years ago, and subsequently defined “centrocytic lymphoma” in the Kiel classification, 2 but MCL was finally accepted as a separate entity only in the early 1990s, when it became evident that …
R-DHAP Cancer information Cancer Research UK
WebAbstract: Mantle cell lymphoma (MCL) is a rare B-cell lymphoma, with a median survival of only three to four years. In recent years, the development of new drugs and therapeutic strategies appeared to have improved the outcomes. ... (R-CHOP alone or alternating with R-DHAP) as induction, and will discuss the role of ibrutinib maintenance for ... WebJan 15, 2008 · High-dose chemotherapy with autologous stem-cell transplantation (ASCT) is curative in a proportion of patients with relapsed or refractory aggressive non-Hodgkin lymphoma (NHL). 1 In general, the 5-year overall survival is 30% to 50%. Different parameters have been identified that have important impact on the overall survival results. drug induced myocarditis
NSSG Chemotherapy Protocol - R-DHAP
WebBackground: The R-DHAP regimen (rituximab, cisplatin, dexamethasone, and high-dose … WebSep 21, 2024 · In The Lancet Haematology, Steven Le Gouill and colleagues1 describe … WebIntroduction: In patients with mantle cell lymphoma (MCL), long-term remissions can be achieved by stem cell transplantation (SCT). Different conditioning treatment protocols exist with or without total body irradiation (TBI). There are few data published on the role of TBI before autologous stem cell transplantation (autoSCT) or allogenic stem cell … combination fan limit switch