Web13 de abr. de 2024 · Objective Intriguingly, hyperinsulinemia, and hyperglycemia can predispose insulin resistance, obesity, and type 2 diabetes, leading to metabolic … Web25 de set. de 2013 · Mitochondrial quality control is fundamental to all neurodegenerative diseases, including the most prominent ones, Alzheimer’s Disease and Parkinsonism. It is accomplished by mitochondrial network dynamics – continuous fission and fusion of mitochondria. Mitochondrial fission is facilitated by DRP1, while MFN1 and MFN2 on the …
OPA1 (D6U6N) Rabbit mAb Cell Signaling Technology
Web14 de jun. de 2010 · The duplicated exons 7-9 of the mutant OPA1 allele result in an in-frame duplication of 102 amino acid residues within the GTPase domain of the OPA1 protein (p.L227_K328dup102), that is expected to increase its molecular weight by 11.8 kDa. Web14 de abr. de 2008 · In order to correlate the individual OPA1 proteins bands that migrate with apparent molecular weights of 80–100 kDa with specific OPA1 isoforms, we immunoprecipitated OPA1 protein from purified mitochondria of mouse brain, heart, liver, and kidney and performed peptide mining. images of small potting sheds
Optic Atrophy Type 1 - PubMed
WebLane 1 is 10% input. Confocal immunofluorescent analysis of ACHN cells using DRP1 (D6C7) Rabbit mAb (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5 ® #4084 (fluorescent DNA dye). 1/3 Image Gallery Learn more about how we get our images To Purchase # 8570 ADD TO BASKET Custom Formulation Web26 de nov. de 2024 · Optic Atrophy 1 (OPA1) is a mitochondrially targeted GTPase that plays a pivotal role in mitochondrial health, with mutations causing severe mitochondrial … WebThree major GTP-binding protein families include trimeric and low molecular weight G-proteins, as well as a family of large proteins homologous to dynamin. The dynamin family contains proteins with diverse structure and function, but highly homologous N-terminal GTPase domains. A subgroup of the dynamin G-protein-binding family includes the … images of small powder room ideas